What are the Applications of Thin Layer Chromatography - TLC ?

 Some of the applications of thin layer chromatography - TLC are discussed below. So let us check out the applications to learn more about TLC.

Some of the Applications of TLC are:

  1. Thin-layer chromatography is ideal for quick screening of plant extracts, dyes, and pharmaceutical compounds.
  2. TLC can separate pigments and chlorophylls in plant extracts for botanical studies.
  3. It identifies synthetic and natural dyes in textiles and artworks.
  4. It is also used to detect counterfeit drugs by comparing standard and sample compound profiles.
  5. TLC is used in teaching labs to demonstrate compound separation visually.
  6. It monitors the reaction progress in organic synthesis through spot comparison.
  7. In herbal medicines it also analyzes alkaloids, essential oils, and phenolic compounds.
  8. TLC compares purity of pharmaceutical samples using reference standards.
  9. It is generally employed in food testing to identify colorants and sweetener adulterants.
  10. It also serves as a low-cost method for preliminary compound identification in field labs.
  11. It also distinguishes similar-looking chemical compounds based on Rf values and solvent mobility.