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 Some of the applications of column chromatography are discussed below. So let us check it out its applications to know more about column chromatography.  Some of the applications of column chromatography are: Column chromatography is used to purify compounds in organic synthesis and chemical industries. It separates reaction products from unreacted starting materials in organic chemistry.  It purifies synthesized compounds by passing solvent mixtures through silica-packed columns.  It isolates natural products such as alkaloids, terpenes, and plant extracts.  Column chromatography also removes color impurities from industrial chemical batches.  It is used in labs to prepare pure compounds for spectral analysis.  It helps to recover pharmaceutical intermediates during multi-step drug synthesis.  Column chromatography fractionates mixtures into individual components by polarity and affinity.  It is applied in dye and pigment industries for pur...

 Some advantages and disadvantages of column chromatography are discussed below. So let us find out its advantages and disadvantages to know more about column chromatography. Advantages of Column Chromatography are: Column chromatography enhances detection of compounds. Column chromatography enables trace analysis. Increases signal to noise ratio It also detects low concentration. Column chromatography improves analytical accuracy. It is best suitable various detection methods. Column chromatography optimizes sensitivity easily. It separates closely related compounds. Enables detection of impurities. Disadvantages of Column Chromatography are: Column chromatography equipment is expensive.  Costly consumables. The operating cost is high. Column chromatography requires specialized training. It is time consuming process. It is labor intensive technique. Difficult to automate. Requires significate sample for analysis.