Function of internal standard in Gas chromatography

Some points on function of internal standard in gas chromatography are:

  • An internal standard compensates for variations in sample evaporation by reflecting losses that occur before column entry.
  • It adjusts for minor changes in split or splitless injection behavior by responding proportionally under the same injection mode.
  • The internal standard accounts for short-term fluctuations in carrier gas flow by exhibiting parallel response changes during analysis.

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