How Does Column Length Affect Gel Filtration Chromatography?

Points on column length in gel filtration chromatography:

  • Column length influences resolution in gel filtration chromatography by determining how many size-based separation stages occur along the porous matrix. 
  • A longer column provides additional length for differential pore access between molecules of different sizes. 
  • This improves size-dependent separation without altering the separation mechanism.

Find out more details on what is gel filtration chromatography for more information.