How does mobile phase composition affect adsorption in chromatography?

  • In adsorption chromatography, the mobile phase influences adsorption by competing with sample molecules for interaction with the stationary phase surface.
  • A stronger mobile phase reduces adsorption by displacing compounds from the stationary phase more effectively.
  • Changes in mobile phase composition alter adsorption strength and therefore modify the rate at which compounds migrate through the column.

Check it out more details on what is adsorption in chromatography to learn more about it.