How Does Mobile Phase Composition Affect Adsorbents in Chromatography?

Points on mobile phase composition and adsorbents in chromatography:

  • Changes in mobile phase composition influence how readily analytes desorb from the adsorbent surface during chromatography. 
  • A stronger mobile phase reduces surface interactions by competing with analytes for adsorption sites. 
  • This demonstrates that retention occurs specifically at the adsorbent surface.

Also check it out more points on what is adsorbent in chromatography for more information.