Significance of derivatization in gas chromatography
Some points on significance of derivatization in gas chromatography are:
- Derivatization introduces silyl, acyl, or alkyl groups that reduce analyte polarity and promote vaporization.
- It increases analyte compatibility with the carrier gas by forming derivatives that remain in the gas phase during transport.
- Derivatization enables low-volatility compounds to pass through the injector without condensation.
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