What Is Hydrodynamic Volume in Gel Filtration Chromatography?

Points on hydrodynamic volume in gel filtration chromatography:

• Gel filtration chromatography separates molecules according to their hydrodynamic volume rather than their molecular weight alone. 
• Hydrodynamic volume determines how easily a molecule can enter and move through the pores of the gel matrix. 
• Molecules with larger effective sizes therefore experience greater exclusion from the porous structure.

Also find out more information on definition of gel filtration to learn more about it.