What is the purpose of system suitability in HPLC?

Some points on purpose of system suitability in HPLC are:

  • System suitability testing confirms that retention time variation remains within predefined method limits.
  • It verifies that resolution between critical peaks meets minimum acceptance thresholds specified in the method.
  • System suitability checks ensure that peak tailing or symmetry values fall within allowed criteria before analysis.

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