What is the role of system suitability in HPLC?

Some points on role of system suitability in HPLC are:

  • System suitability testing confirms stable pump operation by verifying consistent flow delivery during preliminary runs.
  • It evaluates injector repeatability by measuring variation in retention time and peak area from replicate injections.
  • System suitability checks detector response stability to ensure signal consistency before sample analysis.

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