Why Does Particle Size Matter for Adsorbents in Chromatography?

Points on particle size and adsorbents in chromatography:

• Adsorbent particle size affects chromatographic separation by controlling the available surface area for analyte retention. 
• Smaller particles provide more surface contact sites for interaction with analytes. 
• Increased surface availability reinforces the adsorbent’s function of retaining compounds on its surface.

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