Why Is Gel Filtration Called Size-Exclusion Chromatography?

Points on why gel filtration called size-exclusion chromatography:

  • Gel filtration chromatography is called size-exclusion chromatography because separation occurs through selective exclusion of molecules from gel pores. 
  • Larger molecules are excluded while smaller molecules partially enter the porous matrix. 
  • This exclusion-based behavior defines the core separation principle.

Also check out details on definition of gel filtration chromatography to learn more about it.