How does chromatography isolate bioactive plant compounds?

Points on how chromatography isolate bioactive plant compounds:

• Chromatography separates bioactive fractions from crude plant material for further pharmacological and toxicological testing.
• The crude extract is systematically fractionated so that each group of compounds can be screened individually for biological activity.
• Active fractions are then purified and characterized to identify lead molecules for natural drug discovery programs.

Also check it out related article on importance of chromatography in pharmacognosy for more information.