How does GPC calculate molecular weight?
Points on GPC and molecular weight calculation:
- In GPC or Gel Permeation Chromatography analysis, molecular weight distribution is calculated by comparing sample retention times with polymer standards of known molecular size.
- Calibration curves are generated using reference polymers with narrow and well-defined molecular weight distributions.
- These calibration relationships convert chromatographic retention data into accurate number-average and weight-average molecular weight values.
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