What is Partition Chromatography? Definition and Meaning

Definition of Partition Chromatography

• Partition chromatography is a chromatographic technique in which the components of a mixture are separated based on their differential partitioning between a stationary liquid phase and a mobile phase. 
• In partition chromatography, the stationary phase is a liquid immobilized on a solid support, establishing a liquid–liquid separation system within the chromatographic setup. 
• Separation occurs because solute molecules distribute differently between the stationary liquid phase and the moving mobile phase according to their solubility. 
• The fundamental basis of partition chromatography is equilibrium partitioning, in which each component repeatedly transfers between the two phases as the mobile phase flows.