Why Do Chemists Use Column Chromatography in Laboratories
Points on use of column chromatography in lab:
- Column chromatography exploits the distinct binding affinities of various molecules toward the adsorbent bed as they travel with the liquid carrier, enabling chemists to isolate target compounds from complex sample matrices through selective retention mechanisms.
- The selective retention of specific molecules based on their chemical properties allows pharmaceutical isolation, natural product extraction, and impurity removal, with each application relying on the differential affinity between analytes and the solid support to achieve purification.
- The versatility and reliability of this method make it indispensable across all chemistry disciplines.
Also check it out more details on what is column chromatography to learn more about it.