How Do Solvation Effects Drive Separation in Partition Chromatography?

Some points on how do solvation effects drive separation in partition chromatography:

• Minor polarity differences translate into distinct migration behavior in partition chromatography due to selective solvation effects.
• Each compound experiences a different solvation preference between the stationary and mobile liquid phases, altering its effective partition coefficient.
• As these solvation-driven preferences repeat throughout the column, small polarity variations expand into clearly separated migration paths.

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