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Importance of Normal Phase Chromatography
Some points on normal phase chromatography are:
- Normal phase chromatography is important because it separates compounds based on polarity and provides selective retention of polar analytes.
- It enables effective analysis of highly polar compounds unsuitable for reversed-phase methods.
- It supports reproducible characterization of polar functional groups without chemical derivatization requirements.
- This method simplifies early-stage screening of compound polarity differences in complex samples.
- It provides consistent performance for polar analytes using straightforward solvent systems.
- It expands analytical coverage by complementing reversed-phase techniques in polar compound analysis.