Why is column chromatography applied in industrial purification workflows?

Some points on why column chromatography applied in industrial purification workflows:

  • In industrial settings, column chromatography is used to obtain purified substances so that manufacturing processes maintain consistent composition and product quality.
  • Minor variations in impurity levels can propagate into large inconsistencies during scale-based production.
  • For this reason, column chromatography functions as a stabilizing step rather than a final corrective measure.

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