What is the function of degassing in HPLC?

Some points on function of degassing in HPLC are:

  • Degassing lowers dissolved gas concentration to levels below bubble nucleation thresholds under HPLC operating pressures.
  • It prevents pressure-induced outgassing by ensuring solvents enter the pump in a gas-free state.
  • Degassing maintains consistent solvent compressibility by eliminating dissolved gas contributions.

Find out related article on importance of degassing in HPLC to learn more about it.