What is role of degassing in HPLC?

Some points on role of degassing in HPLC are:

  • Degassing reduces the concentration of dissolved air in the mobile phase before it enters the high-pressure pump.
  • It removes oxygen and nitrogen that can come out of solution when pressure conditions change inside the HPLC system.
  • Degassing limits gas solubility effects that occur when solvents are compressed during pumping.

Also check it out importance of degassing in HPLC to learn more about it.