What is the significance of degassing in HPLC?

Some points on significance of degassing in HPLC are:

• Degassing minimizes gas release caused by temperature fluctuations that alter solvent gas solubility.
• It prevents dissolved gases from nucleating into microbubbles within solvent lines and pump chambers.
• Degassing stabilizes the mobile phase composition by maintaining uniform solvent properties free from entrained gases.

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