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Advantages and Disadvantages of HPLC

 Some advantages and disadvantages of high performance liquid chromatography are discussed below. So let us check it its advantages and disadvantages to know more about HPLC. Some advantages of HPLC chromatography: HPLC has high resolution and speed of analysis. High surface area. It has high pressure gradient. It has wide range of stationary phases. Precise flow rate control. Senstive detection methods. Low sample method requirement. Accurate peak identification using HPLC.  Some disadvantages of HPLC chromatography HPLC has high cost. High quality components are needed. The solvents and columns used in HPLC are expensive.  Regular maintenance and calibration is needed which add extra cost.   Sophisticated software is required for data analysis. Research and development cost.

Advantages and Disadvantages of Chromatography

 Some advantages and disadvantages of chromatography are discussed below. So let us check out its advantages and disadvantages to know more about chromatography. Some Advantages of Chromatography are: Chromatography can separate complex mixtures with great precision. High resolution and sensitivity. It can handle small sample sizes. Fast analysis method. It separate compounds based on their chemical properties.  Different compound moves at different speeds.  It is suitable for a wide range of compounds.  Chromatography can separate isomers and enantiomers. It allows easy quantification. Chromatography is versatile and adaptable to different needs. Some Disadvantages of Chromatography are: Chromatography method is expensive.  Costly materials and equipments are used. It requires skilled personnel and maintenance. Chromatography needs specific conditions and environments. Initial investment can be high.  Chromatography continuously needs solvents and gases. H...

Advantages and Disadvantages of Gas Chromatography (GC)

 Some advantages and disadvantages of Gas Chromatography are discussed below. So let us check it out its advantages and disadvantages to know more about gas chromatography. Advantages of Gas Chromatography GC are: Gas chromatography has high resolution power compared to other methods. GC has high sensitivity. High peak capacity. Gas chromatography has high accuracy and precision. It can separate complex mixtures. It is used to resolve closely related compounds. Small sample volume can be separated using gas chromatography. Quantitative analysis is possible using GC. GC can be coupled with mass spectrometry. Disadvantages of Gas Chromatography GC are: Gas chromatography is limited to volatile compounds. Non-volatile compounds don't vaporize. Analyte can decompose at high temperature. Analyte can also react with stationary phase. It is limited to low to medium molecular weight. It is incompatible with aqueous samples. Thermal stability is required during separation through gas chroma...

How could thin layer chromatography be used to aid in the identification of a compound?

 Thin layer chromatography (TLC) is a technique used to separate and identify components of a mixture. It is commonly used in organic chemistry to identify unknown compounds. In TLC, a stationary phase (such as a glass or plastic plate) is coated with a thin layer of adsorbent material. When the mixture is applied to the plate, the different components of the mixture separate based on their relative affinities for the stationary phase. By comparing the positions of the components on the plate to standards, it is possible to identify the components in the mixture.

Why did the liposomes fluoresce during size-exclusion chromatography?

Liposomes fluoresce during size-exclusion chromatography because they contain fluorescent compounds. These fluorescent compounds are often incorporated into the liposomes during the manufacturing process in order to provide a way to track the size of the liposomes as they pass through the chromatography column. The fluorescent compounds can be detected by a detector, which then provides information about the size of the liposomes. 

What is the role of producer top management and QAS towards quality assurance in BRD?

 The role of producer top management and QAS towards quality assurance in BRD is to establish a clear quality assurance policy and objectives. They should also ensure that adequate resources are allocated to quality assurance activities and that these activities are carried out in a systematic and planned manner. Furthermore, they should monitor the effectiveness of quality assurance activities and take corrective action where necessary.

What questions are asked by managers of pharmaceutical companies of their quality assurance people?

 1. What quality assurance procedures does your company have in place? 2. How do you ensure that your products meet quality standards? 3. What are your procedures for investigating quality issues? 4. What quality metrics do you track? 5. How does your company handle non-conforming products? 6. What corrective and preventative actions have you taken in response to quality issues? 7. What trends are you seeing in your quality data? 8. How has your quality management system evolved over time? 9. What challenges do you face in maintaining quality standards? 10. What role do quality assurance personnel play in your company's operations?

Full Form of API in Pharma Industry

FULL FORM OF API What is the full form of API in pharma industry? Answer: Active Pharmaceutical Ingredient API is the central ingredient or the main ingredient used in medicines or pharmaceutical products. Substance other than API are called excipients. In simple words we can say that API is the chemical used in medicine which causes direct effect on the disease.

Difference Between Antibiotics and Antibacterial

The Difference Between Antibiotics and Antibacterial: Let us check it out difference between antibiotics and antibacterial, to know more about Antibiotics and Antibacterial. Difference Between: Antibiotics Antibiotics is the broad term, broader range of antimicrobial compounds which acts on bacteria, fungi and other compounds. Certain Antibiotics may also kills bacteria, Fungi and other parasites. Antibiotics is a chemical substance which kills and prevents the growth of the microorganisms by affecting the cell wall and cell structure of bacteria or fungi. Difference Between: Antibacterial Antibacterial is a types of antibiotics.  Chemical substances or anything that kills bacteria or prevents the growth of bacteria can be considered as antibacterial. All antibacterials are antibiotics but not all antibiotics are antibacterials.

Difference Between Antibiotics and Antibodies

Overview of the Difference Between Antibiotics and Antibodies. Let us find out difference between antibiotics and antibodies to know more about Antibody and Antibiotic. Difference Between: Antibiotic The chemical structure of antibiotic is different from antibody or antibodies. Antibiotics are either synthetic or  produced from plants or other microorganisms,  and they are purified to prevent infection caused by bacteria. Antibiotic attacks the cell wall and prevents the cellular functions of the bacteria. Antibiotic are like medicines that kills other bad cells in the body. Example ampicillin, penicillin. Difference Between: Antibodies The chemical structure of antibodies of antibody is made up op two large protein chains called heavy chains and two small protein chains called light chains which are bound to each other. Antibodies are produced naturally by an immune system in the body. Antibodies binds with the antigen found on the pathogens and prevent inf...

Difference Between Antibiotics and Antiseptics

Overview of Difference Between Antibiotics and Antiseptics. Let us check it out difference between antibiotics and antiseptics to know more about Antibiotics and Antiseptics. Difference between: Antibiotics Antibiotics are the chemical substances which prevent growth and development of microorganisms by killing them. Antibiotics are effective only against bacteria. Antibiotics may be applied internally as well as externally. During surgical procedure to prevent infections, antibiotics are usually applied. Examples of antibiotics: penicillin, neomycin, streptomycin etc. Difference Between: Antiseptics Antiseptics also prevents the growth and development of microorganisms but not necessarily kills them. Antiseptics are effective against wide range of microorganisms. Antiseptics are applied externally. Antiseptics are generally applied on skin and wound surface for cleaning purpose and prevents further growth of microorganisms.  Examples of antiseptics: Hydrogen Pe...

ADVANTAGES AND DISADVANTAGES OF CONDUCTOMETRY IN CHEMISTRY

Conductometry : Let us discuss advantages and disadvantages of Conductometry. This method is also called as conductometric titration method. Types, mobility, concentration of ions and temperature affects the electrochemical conductivity Some of the advantages of conductometry are as follows: In this method as coductance  is measured by conductivity meter , indicator is not required. Conductometric titration works for coloured solution. Accurate results can be obtained by conductometry. It is suitable for both weak base as well as weak acid. This method is also suitable for turbid solution. Some of the disadvantages of conductometry are as follows: Sometimes the salt level increases in the solution which masks the conductivity and do not gives accurate result. Sometimes high concentration of ions masks the conductivity and hence do not give accurate results.

Applications of Conductometry

Some applications of conductometry are discussed here, conductometry in analytical chemistry is used to measure the progress of chemical reactions. Conductometric titration is carried out in order to measure the  electrical conductivity of the reaction mixture. This type of titration gives a sharp end point for the colored solution. This type of titration is used to check water pollution in lakes as well as rivers. It is also used to check the alkalinity of the fresh water Salinity of the sea water can also be checked by this method. It is also used to trace antibiotics. Used for tracing microorganism in food microbiology To check the solubility of sparingly soluble salts. Purity of distilled water and de ionised water can determined.

Vitamin C: Seven Advantages of Vitamin C

Some important Vitamin C points Wednesday, 25 June, 2014 Seven Advantages of Vitamin C Vitamin C has significant advantages over others and is very helpful to cure disease and to keep body healthy. The Advantages of Vitamin C are: Vitamin C in skin protection Vitamin C protects the skin from free radicals which can be generated during exposure of sunlight. The antioxidant present in Vitamin C protects the body skin from harmful ultraviolet radiation during sunlight exposure. Vitamin C to loose fat One of the most significant advantages of Vitamin C is it reduces body fat , vitamin C obtained from fruits are very useful to loose body fat. Doctors says that As Vitamin C lowers the insulin so instead of storing sugars into body and converting into body fat , it uses it as a fuel to reduce fat in the body. Vitamin C in hair loss Vitamin C keeps free radical away which may generate during food intake. The antioxidant property of Vitamin C removes free radical which may cause d...

chromatography: Seven Advantages Of Chromatography

Some important Chromatography points Wednesday, 25 June 2014 Seven Advantages of Chromatography Chromatography has significant advantages over other methods that makes it suitable for identification of unknown component from a mixture. The advantages of Chromatography are: Chromatography is quick method Chromatography is quick method for the separation of various components from a mixture of  various compounds which are difficult to separate. Chromatography is simple Chromatography is simple method and even a single person can operate the instrument or an equipment. Chromatography is accurate One of the most significant advantages of Chromatography is its ability to separate the sample mixture easily and gives accurate results.The ability to separate even complex mixture of compounds effectively, chromatography is widely used method and has applications in various fields. Chromatography is continuous process Chromatography also supports continuous operation for a larg...

APPLICATIONS OF BIOTECHNOLOGY

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  Biotechnology  applications and uses also know as (Biotech) are discussed here. As we know that biotechnology is used in various fields such agriculture , food industry, medicine, pharmaceutical industry and much more. Today various products are prepared using this technology. Various techniques such as genetic engineering, gene therapy , genetic testing are used with the help of biotechnology. Various hybrids of plants, animals, poultry with high nutritional value can be produced with this technique. Various disease can be diagnosed as well as treated with the help of this method So let us discuss different uses of biotechnology one by one. Applications of Biotechnology Biotechnology uses in Food industry Various types of food products are prepared using biotechnology such as bread, beer and wine. Cheese and other products of cheese are also prepared using this technique. It is also used to prepare fruit and vegetables juices. Biotechnology uses in medicine Som...

Applications of Biotechnology in agriculture

Applications of biotechnology in agriculture : There are many uses of biotechnology in various fields such as medicine, food industry, pharmaceutical industry and more. Out of this, It also plays in important role in agriculture. So let us check it out some of the applications of biotechnology in agriculture which are as follows. Diseases resistant crops can be made using biotechnology. Plant which are grown using biotechnology are used in production of various biopharmaceuticals to treat various disease. Plants are also used to create antibiotics which can be used for both animals and humans. Plants can be made which are resistant to various environmental stresses such as cold, heat or drought. Improves yield of crops by introducing various genes which are resistant to insects and are tolerance to herbicides. Nutritional value of plants can be increased by biotechnology. Other useful article: Applications of Biotechnology

Practical Applications of Biotechnology

Practical applications of biotechnology , There are many uses of biotechnology which are used in various different fields such as agriculture, medicine, pharmaceutical industry, food industry, etc. Biotechnology is widely growing field now a days, so let us check is out some of the practical applications of biotechnology which are as follows. Bio processing technology in which using whole cells or the part of cells or the component of cells desired products can be made. An example of whole cell such as yeast or bacteria are used to prepare various products. Most components which are used such as enzymes which acts as catalyst and increases chemical reaction. Cells which are isolated from the animals or plants are used to make desired products. Using genetic engineering various information of genes can be studied. Genetic testing is used to detect disease in children or their parents. Agriculture application of biotechnology for better crops and improved animal health. Some ...

Environmental Applications of Biotechnology

Environmental applications of biotechnology , As we know that now a days biotechnology is widely used in various fields such as agriculture, food industry, pharmaceutical industry, medicine and much more. Out of this biotechnology also plays an important role to protect environment. Some of the environmental applications of biotechnology are as follows. Biotechnology produces enzymes which is used in laundry detergents. Genetically modified microorganisms are made using biotechnology which are used to break industrial waste. It improves manufacturing of products and reduces the waste products. Biotechnology develops bio degradable products. Other article: Applications of biotechnology

Applications of Biotechnology in Food Industry

Applications of biotechnology in food industry : It is used in various fields such as medicine, pharmaceutical industry, agriculture etc., Biotechnology also plays an important role in food industry. So let us check it out some of the application of biotechnology in food industry which are as follows. Use of yeast is industries which can be used for production or preparation of alcohol which is the first product made by using biotechnology. Wine can be prepared by using biotechnology. Fruit and vegetable juices can be prepared by biotechnology. Biotechnology can be used to prepare cheese and other cheese products. Biotechnology can be used to prepare bread. Also visit: Applications of Biotechnology